Delaware's Senator Joe Biden met with the American Iranian Council, and offered to speak with Iranian law makers to find ways to bring improved relations between Iran and the United States.
Washington and Tehran found common ground to cooperate on Afghanistan, and Bush has continued to offer Iran talks. But some believe he undercut that position by lumping Iran in the "axis of evil" during his State of the Union speech this year.
Biden said improved ties with Iran were in U.S. interests, given the Islamic republic's importance to a region studded with oil-rich nations.
The United States was not in a position to have a major impact on Iran's internal power struggle and it should not intervene in any way, the senator said.
Washington must show Iran's youthful population it was "squarely with the Iranian people in their desire to have a democratic government and a democratic society," he said.